Anticoagulants, antiplatelets and thrombolytics
نویسندگان
چکیده
منابع مشابه
Thrombolytics, anticoagulants, and antiplatelet agents.
Thrombolytics The key publication on thrombolytic therapy in acute ischemic stroke using recombinant tissue plasminogen activator was published almost 10 years ago, which led to the approval of this drug in many countries.1 Since then, considerable knowledge has been gained about the risks and benefits of thrombolytic therapy. However, 1 major concern is still the limited time window of 3 hours...
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Anticoagulation is the cornerstone of therapy in patients with ischemic cardiovascular disease. In patients who develop an acute coronary syndrome, following percutaneous coronary interventions, or with an acute ischemic stroke, the rupture or injury of an atherosclerotic arterial plaque serves as a nidus for platelet aggregation and thrombus formation, which, in turn, may cause myocardial infa...
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Decreasing the bleeding risk associated with gastrointestinal (GI) endoscopic procedures and minimizing the thromboembolic risk of withdrawing medications are very important for the patients taking anticoagulants and antiplatelets. Western guidelines on managing anticoagulation and antiplatelet medications in GI endoscopy suggest a polypectomy with aspirin medication or a biopsy with warfarin m...
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OBJECTIVE To compare the effects of antiplatelets and anticoagulants on stroke and death in patients with acute cervical artery dissection. DESIGN Systematic review with Bayesian meta-analysis. DATA SOURCES The reviewers searched MEDLINE and EMBASE from inception to November 2012, checked reference lists, and contacted authors. STUDY SELECTION Studies were eligible if they were randomised...
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Many therapeutic drugs have been identified that possess clinically important antiplatelet activity. Platelet inhibition can be achieved in numerous ways (Fig. 1), including inhibition of platelet cyclooxygenase, inhibition of ADP receptors or inhibition of the platelet glycoprotein (GP) IIb/ IIIa receptor. Pharmacological inhibition of platelet function can also be achieved by interference wit...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2004
ISSN: 0306-5251,1365-2125
DOI: 10.1111/j.1365-2125.2004.02180.x